By establishing the ICP-MS determining method, we determined the contents of Mn, Fe, Cu, Zn, Cr, As, Cd and Pb in the three kinds of ZheJiang specific medicinal materials before and after processing them. The recovery ratio with standard addition of the method is between 95.2％and 106.3, and the relative standard deviation between 0.69％and 2.34％. The results of the experiment show that the contents of useful metals Mn, Fe, Cu and Zn are fairly high both before and after processing, while the contents of harmful heavy metals Cd, Cr, Pb and As are all lower than the limited quantity in the standard of Chinese Pharmacopoeia. After processing, there seems to be some content changes in the trace elements and heavy metals. Different content changes depend on different processing methods. After processing, except the notable decrease in Pb, the contents of Cu, As and Cd are almost constant, while the contents of other elements are nearly all increased. The result seems to be related with the methods of processing. This experimental result provides us with new scientific foundation for the further research on the relationship between different processing methods and different efficacy of the three specific Zhejiang medicinal materials.