Five phases ozone monitoring instrument(OMI) NO2 column density data and Back Trajectory Model (HYSPLIT4) were used to simulate and analyze an NO2 pollution event around the APEC meeting, Beijing, November, 2014. The results show that the spatial distribution of NO2 vertical column density was extremely uneven before APEC. The high-value were distributed in surrounding of Beijing and Tianjin, the mid-value were distributed in its south areas, north and northwest is the low value area. The high value concentration in Beijing, Tianjin and the southern region showed a decreasing trend from south to north during APEC; the range of high value area expanded northward to the central and southern areas of Beijing and Tianjin after APEC. Compared with concentration a week ago, density of NO2 in Xingtai and Handan, which are in south of Beijing-Tianjin-Hebei region, had showed a trend of rising, and concentration in another places had fallen 42% during the APEC. According to back trajectory analysis based on HYSPLIT, the import of NO2 pollution comes from Tangshan, Tianjin before APEC. During the period of APEC, the pollution comes from Russia, Mongolia region. After the APEC, Beijing, Tianjin, Taiyuan and the Southwest are the main NO2 sources areas.