A scheme for generation of frequency quadruple optical millimeter-wave signal to overcome chromatic dispersion is proposed. With radio frequency signal phase, bias, modulation index, and base-band signal gain adjustment, a dual-drive Mach-Zehnder modulator is used to generate frequency quadruple optical millimeter-wave signal only carried by one second-order sideband which solves the problem of time shift of code caused by chromatic dispersion, so the transmission distance is extended greatly. Theoretical analysis and simulation results show that the eye diagram keeps open and clear even when the optical millimeter-wave signals are transmitted over 120 km and the power penalty is about 0.45 dB after fiber transmission distance of 60 km. Furthermore, due to one pure optical component carrying no signals, a full duplex radio-over-fiber (RoF) link based on frequency reuse is also built to simplify the base station. The bidirectional 2.5 Gbit/s data is successfully transmitted over 40 km standard single mode fiber with less than 0.6 dB power penalty in the simulation.