A high efficient conversion from the Ti: Sapphire laser to the Raman laser with 1053 nm wavelength at the area of picosecond (ps) pulse duration is reported. A Ti:Sapphire laser (808 nm wavelength,450 ps pulse duration and 10 mJ pump energy) is employed as the pump source, acetone is stimulated to generate first-order Stokes wave with 1053 nm central wavelength. Inserting Ndglass as a fluorescence enhancement medium, the first-order Stokes wave is obviously enhanced, the energy conversion efficiency from pump laser to the first-order Stokes wave reaches to 17.5％, the bandwidth of the first-order Stokes is 25 nm, and the pulse duration is 318 ps. The physical mechanism together with the potential applications are discussed.