An One-Wire-Interface(OWI) based on Advanced Peripheral Bus(APB) is designed. APB bus can configure the data and read the status information of the interface, with strong flexibility and monitoring ability. The interface realizes half-duplex two-way communication between master and one or more slave devices through a common data line. Compared with other communication interfaces, OWI can save I/O port resources and reduce hardware costs. Based on the one wire transmission protocol, the data transmission sequence and state machine are designed. Through Register Transfer Level(RTL) simulation and Field Programmable Gate Array(FPGA) verification, the results show that the data can be stably and correctly transmitted through OWI and the data transmission rate can reach 100 kHz.