Recently, turquoise from Hami, Xinjiang Provence has been discovered with gem quality and large quantity. In this work, turquoise samples from Hami, Xinjiang were studied with X-ray diffractometer (XRD), laser ablation inductively coupled plasma mass spectrometer (LA-ICP-MS), scanning electronic microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy (Raman), and ultraviolet-visible spectroscopy (UV-Vis) to obtain the mineralogy and spectra characteristics. The chemical composition of turquoise from Hami was characterized by rich Cr (1 617 ppm), V (435 ppm), Ti (428 ppm) and poor Ba (99.9 ppm). And, the color of turquoise gradually changed from green to blue with the decrease of the rate of Fe2O3/CuO. The SEM results showed that the turquoise crystals were mainly needle, columnar and long plate shape with the size of 0.2～3 μm. The infrared and Raman spectra of turquoise were induced by the vibration of phosphate group (located at 1 000~1 200 and 420~650 cm-1), hydroxy group (located at 3 400~3 600 cm-1) and crystal water (located at 3 000~3 300 cm-1). Besides, the UV-Vis spectra of the turquoise samples showed that the absorption peaks at 430 nm and 600~700 nm belonged to the electron transition of Fe3+and Cu2+, respectively.