In order to improve the utilization rate of solid wastes such as fly ashslagiron tailing sand and manufactured sand and prepare early strength and slightly expansive high-strength grouting material the mechanical properties and microstructure of grouting materials were analyzed under the joint action of solid waste composite materials by mixing ordinary Portland cement and sulphoaluminate cementdesigning the ternary composite system of quartz sandiron tailing sand and manufactured and orthogonal test. The test results show that the optimal mass mix ratio of ordinary Portland cement and sulphoaluminate cement is 4∶1the optimal mass mix ratio of quartz sandiron tailings sandlimestone manufactured sand is 7∶1∶2and the influence degree of four factors on strength of grouting materials from large to small in the orthogonal test is water binder ratiofly ash contentbinder sand ratio and slag content. Through range analysisthe optimal factor level combination is water binder ratio is 0.33binder sand ratio is 1.0∶1.2and the fly ash content and slag content are 6% and 10% (mass fraction)respectively. Through the analysis of XRD and SEMit is found that the density of C-S-H gel will affect the strength of grouting material. The water binder ratio has an effect on the phase of ettringiteand ettringite and tricalcium aluminate hexahydrate can improve the early strength of specimens.