The opto-electronic load is an important reconnaissance equipment of the UAV system.To obtain a clear image, a new opto-electronic load control strategy is proposed for inhibiting the disturbance of visual axis.First, the structure and working principle of the two-axis and two-frame opto-electronic load are introduced.Then, analysis and classification are made to the disturbance factors affecting the stability of the visual axis.The dual rate-loop control strategy and an active disturbance rejection controller are applied on the opto-electronic load.The experimental results show that, the opto-electronic load using the proposed line-of-sight stabilization strategy can satisfy the technical requirements of disturbance rejection.