Multi-functionalization is an important development direction of optical fiber chemosensors. A laser-induced self-written waveguide technique is used to prepare optical fiber-hydrogel polymer waveguide-fiber sensing structures. In this structure, the waveguide is coaxially connected to the optical fibers, which ensures the high efficiency of pumping light launching and signal collection. In order to broaden the sensing abilities of the optical fiber-polymer waveguide-fiber (OFWF) sensor, gold nano-particles (AuNPs) are successfully doped into the waveguide session of the OFWF. The AuNPs-doped OFWF sensor is good at spectral detection. We successfully achieved the absorption, fluorescence and Raman spectra measurement of acriflavine hydrochloride. It is believed that the AuNPs-doped OFWF has great potential in various applications.