Seventy patients with 316 tumors of urinary bladder have been treated by photodynamic therapy (PDT) with a gold vapour laser. All cases were histopathologically diagnosed as transitional cell carcinoma. The power output from the tip of an optic fibre was 2.0～2.5 W and the power density used was 70.8～509.6 mW/cm2. The pulse duration was 20～50 μs, the pulse energy was 0.5 mJ per pulse and the repetition rate was of 6000～9000 Hz. Both the tumors and whole bladder were irradiated. Hematoporphyrin derivative (HpD, Yanzhou Biochemical Pharmaceutics, China was given IV in a dose of 5 mg/kg in 250 ml of 5% glucose, 48 hours prior to irradiation. The results of a follow-up of 4～46 months are as follows: cured, 54 case (77.14%); good effect, 12 (17.14%); and improved, 4(5.7%). Tumor regrowth occurred only in 8 cases (11.43%) within 3～9 months after PDT. The results suggest an increase of cured ratio and a decrease of regrowth ratio and the reoccurrence ratio of tumors has compared with results obtained by other treatment modalities.