Considering the laser applications in biology and medicine as background, this paper presented a theoretical research on the hyperbolic heat conduction in laser irradiated tissue. A numerical model was established by combining the seven-flux model of light propagation with the two-dimensional hyperbolic heat conduction model in cylindrical coordinates. It showed that there exists a great discrepancy between the results obtained by treating the laser irradiation as volumetric absorption (i.e. taking laser scattering and absorption into consideration) and those obtained by treating the laser irradiation as the second boundary condition. The effects of the scattering and absorption coefficients of tissue on the hyperbolic heat conduction in laser irradiated tissue were discussed.