A whispering-gallery-mode (WGM) fiber laser integrated on a polydimethylsiloxane (PDMS) chip is presented which consists of a multimode quartz optical fiber, plastic wedge optical fiber, lasing dye solution, a glass and a PDMS substrate. A multimode quartz unclad optical fiber with a diameter of 279 μm and a plastic wedge optical fiber with a diameter of 200 μm are coupled and fixed on a glass substrate, and the length and width of the glass substrate are 2 cm and 1 cm, respectively. By pouring liquid PDMS on the glass substrate and oven dry, a flexible PDMS substrate (thickness is about 400 μm) is shaped. Then a fiber channel (length is 0.4 cm, both width and height are 400 μm) is carved in the contact position between PDMS and the coupled optical fiber. After injecting ethanol solutions of rhodamine 6G into the channel and packaging by a cover glass, a WGM laser chip integrated on a PDMS substrate is fabricated. Pumped by evanescent wave along the quartz optical fiber axis, low threshold energy of 8.5 μJ and directional WGM lasing emission has been successfully achieved on a PDMS chip.