Aiming at the deficiency which traditional micropump structures are complex, and difficult to fabricate, a novel actuating approach is proposed basing on mechanical effect of laser-induced shock waves, micropump designed by this approach has the characteristics of simple structure, ease to manufacture, low cost and the benefit of miniaturization and integration with micro electro mechanical system (MEMS) system. The modal of surface pressure produced by laser induced shock waves is investigated. The valve-less micropump is designed, and its coupling modal is calculated. The feasibility of this actuated approach is validated. The influence of laser parameters (frequency, duty cycle, intensity, spot diameter) on flow rate is analyzed by the fluid-structure interaction simulation and the stability of flow rate is also investigated. The result reveals that laser intensity and spot diameter are the main influencing factors on the flow rate, flow rate maximizes when duty cycle is 0.6, the difference of flow rate at each single pulse is less than 5% at steady operation.