Huang Shiguang, Jin Xiangyu, Lin Rongzan, Lin Xue, Xue Ning, Fan Yunqian, Zu Guo, Ma Li, Luo Xianbo, Huang Guoliang. Microfluidic Chip Based Nucleic Acid Analyzer and Its Application in Precision Medicine[J]. Chinese Journal of Lasers, 2018, 45(3): 307002
- Chinese Journal of Lasers
- Vol. 45, Issue 3, 307002 (2018)
Fig. 1. Principle diagram of isothermal nucleic acid amplification. (a) Initialization phase; (b) circulatory phase
Fig. 2. Structural diagram of microfluidic chip with 24 channels
Fig. 3. Schematic diagram of nucleic acid analyzer
Fig. 4. (a)(b) Photos of micro-fluidic chip based nucleic acid analyzer; (c) photo of micro-fluidic chip kit
Fig. 5. Results of microfluidic chip based isothermal nucleic acid amplification. (a) Result of sensitivity test; (b) result of linearity test; (c) result of specificity test
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Table 1. Example for gene-specific probes of pathogenic bacteria
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Table 2. Results of clinical sample test
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Table 3. Analysis of discrepancy samples of test result
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