In the present paper a new 5-nitrosalicylaldehyde was prepared by thereaction of salicylaldehyde with mix acid, and this semicarbazide Schiff baseligand and its complex containing Cu(Ⅱ) and Ni(Ⅱ) were synthesized. Itscompositions and structure were characterized by elemental analyses, thermalanalyses,IR spectra and UV spectra,1H NMR and molar conductivity. The dismutationto O－2 free radical was also investigated. The result shows that the structureand thermodynamic properties were stable. The complexes showed a distinct -2scavenging effect and some protective effects on hemoglobin of human erythrocytein the system of -2 generating riboflavin with irradiation.Zinc(Ⅱ)