In order to measure the wave aberration of optical lens with small field of view rapidly and precisely, a new wave aberration measuring system based on both auto-collimation principle and Fizeau spherical laser interferometer measurement principle is described. The wave aberration measurement principle by Fizeau spherical laser interferometer is introduced. The assembling and measuring methods of this new auto-collimation-based wave aberration system are discussed and analyzed in detail. By using the characteristic of auto-collimation optics, the in-terferometer′s axis, the optical lens′s optical axis and the high-precision reflector′s axis are precisely determined, and the fast assembly of the optical system is implemented too. Analyses reveal that this system can be an effective solution to the optical axis deviation problem in measuring the wave aberration of optical lens with small-field of view, and implementing the wave aberration test of optical lens rapidly and accurately.