2060-T8 Al-Li alloy is a new aircraft material with low density, high specific strength and well properties in low temperature conditions. 2060-T8 Al-Li alloy in 2 mm thick is welded by fiber laser with 5087 (Al-Mg-Zr) filler wire. The cracking susceptibility of joints obtained under different welding parameters is investigated. The microstructure and mechanical properties are analyzed as well. The result indicates that, a higher laser power or a larger welding speed causes the increase of crack number, and a lower wire feeding rate results in a higher cracking susceptibility. Under the condition of 3 kW laser power, 3 m/min welding speed and 3 m/min wire feeding rate, the weld with great formation and few welding defects are obtained. The average tensile strength of joints reaches to 309 MPa, and the tensile fractures occur in the weld zone. At the waist of weld, the fine equiaxed grains are in larger quantities and the columnar crystals are more refined than the upside and downside near the fusion line, which resultes from the mode of fluid flow in weld pool and the thickness of the boundary-layer.