• Chinese Journal of Lasers
  • Vol. 50, Issue 3, 0307105 (2023)
Yue Xu1 and Liming Nie2、*
Author Affiliations
  • 1Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China
  • 2Optical Molecular Imaging Laboratory, Research Center of Medical Sciences, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong, China
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    DOI: 10.3788/CJL221142 Cite this Article Set citation alerts
    Yue Xu, Liming Nie. Application of Optical Imaging for Studying Chinese Acupuncture: a Review[J]. Chinese Journal of Lasers, 2023, 50(3): 0307105 Copy Citation Text show less
    Different imaging technologies for studying acupuncture therapy and their application scope
    Fig. 1. Different imaging technologies for studying acupuncture therapy and their application scope
    Continuous display of gastric laser Doppler blood perfusion images of rats during electroacupuncture (EA)[30]. (a) Before EA stimulation; (b) instant of EA stimulation; (c) EA stimulation for 5 min; (d) EA stimulation for 10 min; (e) 5 min after ceasing EA stimulation; (f) 10 min after ceasing EA stimulation
    Fig. 2. Continuous display of gastric laser Doppler blood perfusion images of rats during electroacupuncture (EA)[30]. (a) Before EA stimulation; (b) instant of EA stimulation; (c) EA stimulation for 5 min; (d) EA stimulation for 10 min; (e) 5 min after ceasing EA stimulation; (f) 10 min after ceasing EA stimulation
    Comparison of peak values of group average hemodynamic response between CG and IG for each phase[59]. (a) The first phase (0 week); (b) the second phase (4 weeks); (c) the third phase (8 weeks)
    Fig. 3. Comparison of peak values of group average hemodynamic response between CG and IG for each phase[59]. (a) The first phase (0 week); (b) the second phase (4 weeks); (c) the third phase (8 weeks)
    Maximum amplitude projection (MAP) and corresponding computed vascular centerlines overlaid with segmented volumetric opticalresolution photoacoustic microscopy (OR-PAM) images of GB34, ST36 and non-acupoint sites in the osteoarthritis group (scale bar is 200 μm)[73]
    Fig. 4. Maximum amplitude projection (MAP) and corresponding computed vascular centerlines overlaid with segmented volumetric opticalresolution photoacoustic microscopy (OR-PAM) images of GB34, ST36 and non-acupoint sites in the osteoarthritis group (scale bar is 200 μm)[73]
    PAT images of brain under acupuncture on the left or right GB34 point for a representative normal mouse, where the images are given at different time points and the color scale indicates relative strength of photoacoustic signal[77]
    Fig. 5. PAT images of brain under acupuncture on the left or right GB34 point for a representative normal mouse, where the images are given at different time points and the color scale indicates relative strength of photoacoustic signal[77]
    TechnologySpace resolutionTime resolutionPenetration depthApplication scope
    PAM~5 μm~2 s2-3 mmStructural imaging of microvessels;quantitative analysis of hemodynamic parameters
    PACT3-4 mm~100 ms≥40 mmFunctional and structural imaging of vascular in human muscles,visceras and other deep tissues
    fNIRS2 μm≥40 ms~20 mmDetection of cerebral blood and brain dynamics response;verification of acupoint specificity
    LSI2-3 μm≤10 ms≤1 mmMonitoring local tissue blood perfusion and measuring blood supply of lesion site in real-time
    Table 1. Technical parameters and characteristics of different optical imaging methods and their application scope
    Yue Xu, Liming Nie. Application of Optical Imaging for Studying Chinese Acupuncture: a Review[J]. Chinese Journal of Lasers, 2023, 50(3): 0307105
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