The multipoint calibration method provides high calibration accuracy. However, a reasonable number of calibration points are required in order to achieve the theoretical correction effect. This work proposes an algorithm for selecting multipoint legal punctuation. The algorithm uses the residual as the criterion for selecting calibration points and adaptively determines the calibration points on the focal plane response curve. The non-uniformity of the response rate of the original image collected by the detector and corrected by the proposed algorithm is 0.31%, which is about 31% less than that of the traditional uniform segmented multipoint method. In addition, the correction accuracy of the multipoint method is significantly improved.