• Chinese Journal of Lasers
  • Vol. 49, Issue 20, 2007104 (2022)
Jie Zheng1, Dongyuan Liu1, Qi Zhang1, Limin Zhang1、2, and Feng Gao1、2、*
Author Affiliations
  • 1College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
  • 2Tianjin Key Laboratory of Biomedical Detecting Techniques and Instruments, Tianjin 300072, China
  • show less
    DOI: 10.3788/CJL202249.2007104 Cite this Article Set citation alerts
    Jie Zheng, Dongyuan Liu, Qi Zhang, Limin Zhang, Feng Gao. Mucosal Lesion Diagnosis System Using Joint Sub-Diffusive Domain Diffuse Reflectance and Fluorescence Spectroscopy[J]. Chinese Journal of Lasers, 2022, 49(20): 2007104 Copy Citation Text show less
    Diagram of light transmission in sub-diffusive domain of mucosal tissue
    Fig. 1. Diagram of light transmission in sub-diffusive domain of mucosal tissue
    Schematic and physical picture of system. (a) Schematic of system; (b) physical picture
    Fig. 2. Schematic and physical picture of system. (a) Schematic of system; (b) physical picture
    Schematic of light source module
    Fig. 3. Schematic of light source module
    MC simulation model and results. (a) MC model with two-layer structure ; (b) ratio of number of photons not reaching Z1 depth to that reaching Z1 depth
    Fig. 4. MC simulation model and results. (a) MC model with two-layer structure ; (b) ratio of number of photons not reaching Z1 depth to that reaching Z1 depth
    Optical fiber combined probe. (a) Schematic of probe tip; (b) physical picture
    Fig. 5. Optical fiber combined probe. (a) Schematic of probe tip; (b) physical picture
    Flow chart of system operation
    Fig. 6. Flow chart of system operation
    Mean spectral intensity and standard deviation of spectral intensity . (a) White LED; (b) ultraviolet LED
    Fig. 7. Mean spectral intensity and standard deviation of spectral intensity . (a) White LED; (b) ultraviolet LED
    In vitro tissues of four animals. (a) Porcine muscle; (b) chicken breast; (c) pork belly; (d) pork shoulder
    Fig. 8. In vitro tissues of four animals. (a) Porcine muscle; (b) chicken breast; (c) pork belly; (d) pork shoulder
    Spectral slopes of different tissues at different wavelengths. (a) SDS of 500 μm; (b) SDS of 900 μm
    Fig. 9. Spectral slopes of different tissues at different wavelengths. (a) SDS of 500 μm; (b) SDS of 900 μm
    Spectra of two mucosal tissues. (a) DRS-500; (b) DRS-900; (c) AFS-500; (d) AFS-900
    Fig. 10. Spectra of two mucosal tissues. (a) DRS-500; (b) DRS-900; (c) AFS-500; (d) AFS-900
    Pretreatment methodClassification accuracy /%
    Porcine muscle and chicken breastPorcine muscle and pork bellyPork belly and pork shoulder
    Smoothing10010082
    Normalization10010070
    Table 1. Classification results of three groups of in vitro tissues in full-band spectra
    Characteristic extraction methodClassification accuracy /%
    Porcine muscle and chicken breastPorcine muscle and pork bellyPork belly and pork shoulder
    First derivative10098.580
    PCA10098.874
    Kurtosis+skewness+mean+variance100100.077
    Table 2. Classification results of three groups of in vitro tissues in characteristic band spectra
    Jie Zheng, Dongyuan Liu, Qi Zhang, Limin Zhang, Feng Gao. Mucosal Lesion Diagnosis System Using Joint Sub-Diffusive Domain Diffuse Reflectance and Fluorescence Spectroscopy[J]. Chinese Journal of Lasers, 2022, 49(20): 2007104
    Download Citation