Therapeutic effect of Potentilla anserina L polysaccharide on mice injured by 60Co γ ray irradiation

Daiyan WU; Yangyang FENG; Linzi ZHANG; Qianqian LIU; Hangyu LI; Jianzhenma YANG; Haibo FENG

doi:10.11889/j.1000-3436.2022-0080

Journals >Journal of Radiation Research and Radiation Processing >Volume 41 >Issue 1 >Page 010304 > Article

Journal of Radiation Research and Radiation Processing
Vol. 41, Issue 1, 010304 (2023)

Therapeutic effect of Potentilla anserina L polysaccharide on mice injured by ⁶⁰Co γ ray irradiation

Daiyan WU, Yangyang FENG, Linzi ZHANG, Qianqian LIU, Hangyu LI, Jianzhenma YANG, and Haibo FENG^*

Author Affiliations

College of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu 610041, China

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DOI: 10.11889/j.1000-3436.2022-0080 Cite this Article

Daiyan WU, Yangyang FENG, Linzi ZHANG, Qianqian LIU, Hangyu LI, Jianzhenma YANG, Haibo FENG. Therapeutic effect of Potentilla anserina L polysaccharide on mice injured by ⁶⁰Co γ ray irradiation[J]. Journal of Radiation Research and Radiation Processing, 2023, 41(1): 010304 Copy Citation Text

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Fig. 1. Routine blood analysis: (a) RBC; (b) HGB; (c) HCT; (d)WBC

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Fig. 2. Effects of PAP on the spleen index of mice

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Fig. 3. Effects of PAP on the liver SOD in ⁶⁰Co-γ radiation-induced mice

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Fig. 4. Effects of PAP on the liver T-AOC in ⁶⁰Co γ radiation-induced mice

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Fig. 5. Effects of PAP on the liver MDA in ⁶⁰ Co γ radiation-induced mice

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Fig. 6. Lymphocyte subsets: (a) proportion of CD3⁺ lymphocytes; (b) proportion of CD4⁺ lymphocytes; (c) proportion of CD8⁺ lymphocytes

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Fig. 7. Compared with 0 Gy 0.5 mL distilled water, effects of PAP on the DNA coefficient of bone marrow of mice

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组别 Groups	处理方式 Methods	灌胃剂量 /（1次∙d^-1） Gavage dose	灌胃时间 / d Gavage time
1	不照射 Not irradiated	0.5 mL蒸馏水 0.5 mL distilled water	5
2	不照射 Not irradiated	0.5 mL蕨麻多糖(150 mg/kg B.W.) 0.5 mL PAP (150 mg/kg B.W.)	5
3	不照射 Not irradiated	0.5 mL蕨麻多糖(300 mg/kg B.W.) 0.5 mL PAP (300 mg/kg B.W.)	5
4	不照射 Not irradiated	0.5 mL蕨麻多糖(600 mg/kg B.W.) 0.5 mL PAP (600 mg/kg B.W.)	5
5	5 Gy γ 射线照射，剂量率为0.8 Gy/min 5 Gy γ ray irradiation with a dose rate of 0.8 Gy/min	0.5 mL蒸馏水 0.5 mL distilled water	5
6	5 Gy γ 射线照射，剂量率为0.8 Gy/min 5 Gy γ ray irradiation with a dose rate of 0.8 Gy/min	0.5 mL蕨麻多糖(150 mg/kg B.W.) 0.5 mL PAP (150 mg/kg B.W.)	5
7	5 Gy γ 射线照射，剂量率为0.8 Gy/min 5 Gy γ ray irradiation with a dose rate of 0.8 Gy/min	0.5 mL蕨麻多糖(300 mg/kg B.W.) 0.5 mLPAP (300 mg/kg B.W.)	5
8	5 Gy γ 射线照射，剂量率为0.8 Gy/min 5 Gy γ ray irradiation with a dose rate of 0.8 Gy/min	0.5 mL蕨麻多糖(600 mg/kg B.W.) 0.5 mL PAP (600 mg/kg B.W.)	5

Table 1. Groups and plan

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