In order to meet the requirements of the next generation 6G network for large capacity,high speed and low delay on optical fiber transmission system,a second-order multi-pumping Raman fiber amplifier is designed by using quartz fiber as transmission medium and artificial bee colony algorithm.The Runge Kutta method and the shooting method are used to solve the power coupled wave equation of the second-order multi-pumping Raman fiber amplifier,and then the artificial bee colony optimization algorithm is used to optimize the different arrangement structures of the four pumping beams.Through Matlab simulation,the best bi-directional pumping structure FFBF is obtained from 14 types of bi-directional pumping structures.The average gain of the structure is as high as 24.8 dB in the bandwidth of 100 nm,and the gain flatness is only 0.78 dB,which provides a reference for the design and optimization of Raman fiber amplifier in 6G network.