The stability of open pit slope is greatly affected by blasting vibration.In order to further analyze and study the stability characteristics of open pit slope under blasting vibration, the static stability of open pit slope is analyzedand the displacement, stress and static safety factor of slope under static conditions are obtained.On the basis of static calculation, the dynamic response characteristics of the slope under blasting vibration are calculated, and then the response characteristics such as displacement, stress and dynamic safety coefficient of the slope under blasting load are obtained, which can be used to analyze the stable state of the slope under blasting action.By using ANSYS finite element software, strength reduction method is used to analyze the stable state of the open slope under static and dynamic load.The safety factor under the dead weight of the slope is 1.66, which is in a stable state.The safety coefficients of the slope under different blasting loads are 1.46, 1.5, 1.56 and 1.62 respectively, decreaseingby 2.4%~12% under the static condition.Through the relation between safety factor and horizontal radial vibration velocity, it is deduced that the safety vibration velocity of the south side slope is 10.64 cm/s and the critical vibration velocity is 13.16 cm/s.