A wear resistance multiphase coatings is fabricated by laser cladding of silicon and graphite mixed powders on the substrate of titanium alloy (Ti-6Al-4V). The microstructures and phases in the coatings are investigated by means of electron probe microanalysis (EPMA) and X-ray diffraction (XRD). The results show that a lot of compounds are formed in-situ in the coatings, which are metallurgically bonded to the substrate. The compounds in the coatings are chiefly composed of pre-eutectic SiC, TiC and eutectic Ti5Si3. The test results show that the hardness of the coatings is up to 2000 Hv0.1, much higher than that of the Ti-6Al-4V substrate (about 320 Hv0.1) and the friction coefficient of the coatings is about 0.3, lower than that of the substrate (about 0.55). Changing the parameters of laser cladding has an effect on the properties and microstructures of the claddings. Thus an ideal claddings freeing from the pores and cracks can be obtained by optimizing the cladding parameters.