• Chinese Journal of Lasers
  • Vol. 52, Issue 3, 0307205 (2025)
Xinyu Jiang1, Jing Feng1, Dong Li1,*, Liang Yao2, and Yuping Zheng2
Author Affiliations
  • 1State Key Laboratory of Multiphase Flow in Power Engineering, Xi’an Jiaotong University, Xi’an 710049, Shaanxi , China
  • 2Department of Ophthalmology, The Second Affiliated Hospital, Xi’an Jiaotong University, Xi’an 710004, Shaanxi , China
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    DOI: 10.3788/CJL241218 Cite this Article Set citation alerts
    Xinyu Jiang, Jing Feng, Dong Li, Liang Yao, Yuping Zheng. Heat Transfer Model and Photothermal Conversion in Laser Therapy for Retinal Diseases[J]. Chinese Journal of Lasers, 2025, 52(3): 0307205 Copy Citation Text show less
    Schematic diagram of laser surgery procedure of retinal [29]
    Fig. 1. Schematic diagram of laser surgery procedure of retinal [29]
    Model diagram of full eye structure and porous fundus
    Fig. 2. Model diagram of full eye structure and porous fundus
    Comparison of transient calculation results of coupled full-eye model with experimental results from reference
    Fig. 3. Comparison of transient calculation results of coupled full-eye model with experimental results from reference
    Results after TTT treatment. (a) Full-eye temperature distribution; (b) photoreceptor temperature
    Fig. 4. Results after TTT treatment. (a) Full-eye temperature distribution; (b) photoreceptor temperature
    Temperature distribution of each layer of fundus after TTT treatment. (a) Temperature of retinal neural epithelium stroma; (b) temperature of retinal neural epithelium blood; (c) temperature of RPE stroma; (d) temperature of RPE blood; (e) temperature of choroidal stroma; (f) temperature of choroidal blood
    Fig. 5. Temperature distribution of each layer of fundus after TTT treatment. (a) Temperature of retinal neural epithelium stroma; (b) temperature of retinal neural epithelium blood; (c) temperature of RPE stroma; (d) temperature of RPE blood; (e) temperature of choroidal stroma; (f) temperature of choroidal blood
    Temperature distribution of fundus along pupil axis after TTT treatment
    Fig. 6. Temperature distribution of fundus along pupil axis after TTT treatment
    Results after PRP treatment. (a) Full-eye temperature distribution; (b) photoreceptor temperature
    Fig. 7. Results after PRP treatment. (a) Full-eye temperature distribution; (b) photoreceptor temperature
    Temperature distribution of each layer of fundus after PRP treatment. (a) Temperature of retinal neural epithelium stroma; (b) temperature of retinal neural epithelium blood; (c) temperature of RPE stroma; (d) temperature of RPE blood; (e) temperature of choroidal stroma; (f) temperature of choroidal blood
    Fig. 8. Temperature distribution of each layer of fundus after PRP treatment. (a) Temperature of retinal neural epithelium stroma; (b) temperature of retinal neural epithelium blood; (c) temperature of RPE stroma; (d) temperature of RPE blood; (e) temperature of choroidal stroma; (f) temperature of choroidal blood
    Temperature distribution of fundus along pupil axis after PRP treatment
    Fig. 9. Temperature distribution of fundus along pupil axis after PRP treatment
    Results after SDM treatment. (a) Full-eye temperature distribution; (b) photoreceptor temperature
    Fig. 10. Results after SDM treatment. (a) Full-eye temperature distribution; (b) photoreceptor temperature
    Temperature distribution of each layer of fundus after SDM treatment. (a) Temperature of retinal neural epithelium stroma; (b) temperature of retinal neural epithelium blood; (c) temperature of RPE stroma; (d) temperature of RPE blood; (e) temperature of choroidal stroma; (f) temperature of choroidal blood
    Fig. 11. Temperature distribution of each layer of fundus after SDM treatment. (a) Temperature of retinal neural epithelium stroma; (b) temperature of retinal neural epithelium blood; (c) temperature of RPE stroma; (d) temperature of RPE blood; (e) temperature of choroidal stroma; (f) temperature of choroidal blood
    Temperature distribution of fundus along pupil axis after SDM treatment
    Fig. 12. Temperature distribution of fundus along pupil axis after SDM treatment
    Tissue

    Specific heat /

    (J∙ kg-1∙K-1

    Density /

    (kg∙m-3

    Thermal conductivity /

    (W∙m-1∙K-1

    Thickness

    H /μm

    Cornea417810500.580.45
    Aqueous humor39979960.5782.8
    Iris334011000.4980.35
    Lens399710500.44.25
    Vitreous humor399710000.59415.34
    Retinal nerve417810000.580.21
    RPE419010000.6280.01
    Choroid417810000.580.25
    Sclera318010501.00420.7
    Table 1. Physical and geometric parameters of tissues in coupled full-eye model[7,30,26]
    TissueAbsorption coefficient /m-1Scattering coefficient /m-1Anisotropy factor
    Wavelength of 532 nmWavelength of 810 nmWavelength of 532 nmWavelength of 810 nmWavelength of 532 nmWavelength of 810 nm
    Cornea61.333.22226810500.90.9
    Aqueous humor13.410.410266.380.90.9
    Iris13.410.410266.380.90.9
    Lens3.283.29113.83105.220.90.9
    Vitreous humor1.783.15.015.30.90.9
    Retinal nerve *Blood2530040075610452400.980.98
    Tissue3805822140163400.970.97
    RPE*Blood8900035000140600956000.9950.995
    Tissue3805823150142700.840.84
    Choroid *Blood2530040075610452400.980.98
    Tissue3470112029300186500.870.87
    Sclera310.219.867980292700.90.9
    Table 2. Optical parameters of tissues in coupled full-eye model[29,31]
    Xinyu Jiang, Jing Feng, Dong Li, Liang Yao, Yuping Zheng. Heat Transfer Model and Photothermal Conversion in Laser Therapy for Retinal Diseases[J]. Chinese Journal of Lasers, 2025, 52(3): 0307205
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