Universal Fresnel formulae at the interface of two medium whose permitivity and permeability are ε₁μ₁、ε₂μ₂ are derived from Maxwell theory. The universal Fresnel formulae of the reflectivity and transmission coefficients are given. It is applicable for Right-handed materials and Left-handed materials.Analyzing properties of refection and refraction between two medium,the condition of Brewster angle are given in the Left-handed materials. The condition show that Brewster angle is not only relate to refractive index but also relate to permeability.