To establish a higher performance guide star catalogue, the advantages and disadvantages of existing guide star catalogues were analyzed, a reasonable division method for guide star catalogues was proposed. Following the principle of block space solid angle “Quasi Uniform Distribution”, the method divided the celestial sphere into some sub blocks in a sequence by using a space solid angle corresponding to certain region of the celestial equator for a reference, so that a more uniform distribution of guide star catalogue was achieved. By taking a space solid angle corresponding to the 15°×15 °as an example, the simulation experiment was performed and the results show that the changed scope of maximum sub block and minimal block is 22.86%, the Root Mean Square(RMS) value is 0.0603, and the uniformity is better than that of the inscribed cube method when the space solid angle “quasi uniform distribution” algorithm is used. The proposed method lays a foundation for the rapid generation of star chart and selection of guide star in identification and simulation star chars.