The effect of ultrasonic vibration on the microstructures and mechanical properties of the as-deposited and the solution-aging treated forming parts is investigated during the laser cladding deposition of Ti6Al4V alloys. The research results show that, the ultrasonic vibration during deposition can reduce the surface roughness and residual stress of forming parts, which makes the β columnar grains refined, and the strength and elongation of the forming part increase slightly. As for the forming parts after solution-aging treatment, a mixed structure composed of equiaxed α phase, basket-shaped flaky α phase and converted β phase is formed. However, the grains are still small, the elongation is relatively high, the plasticity increases significantly, and the strength decreases little. The comprehensive mechanical properties overpass the forged part standard.