Study on dose calculation of pelvic tumor radiotherapy planning based on iCBCT images

Qianfeng ZHAO; Xin MING; Bo LIU; Chunhui TANG

doi:10.11889/j.1000-3436.2022-0090

Journals >Journal of Radiation Research and Radiation Processing >Volume 41 >Issue 1 >Page 010303 > Article

Journal of Radiation Research and Radiation Processing
Vol. 41, Issue 1, 010303 (2023)

Study on dose calculation of pelvic tumor radiotherapy planning based on iCBCT images

Qianfeng ZHAO^1、2, Xin MING³, Bo LIU⁴, and Chunhui TANG^1、2、*

Author Affiliations

¹Department of Oncology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, China

²Institute of Oncology, Hubei University of Arts and Science, Xiangyang 441021, China

³School of Biomedical Engineering, Tianjin Medical University, Tianjin 300050, China

⁴Shandong Cancer Hospital, Jinan 250117, China

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DOI: 10.11889/j.1000-3436.2022-0090 Cite this Article

Qianfeng ZHAO, Xin MING, Bo LIU, Chunhui TANG. Study on dose calculation of pelvic tumor radiotherapy planning based on iCBCT images[J]. Journal of Radiation Research and Radiation Processing, 2023, 41(1): 010303 Copy Citation Text

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Fig. 1. Calibrated CT value-relative electron density curves

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Example of isodose curves distribution and DVH plot results: (a) isodose distribution for pCT planning; (b) isodose distribution for iCBCT planning; (c) comparison of DVH diagrams of the two plans (color online)

Fig. 2. Example of isodose curves distribution and DVH plot results: (a) isodose distribution for pCT planning; (b) isodose distribution for iCBCT planning; (c) comparison of DVH diagrams of the two plans (color online)

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Fig. 3. Comparison of differences in CT values between iCBCT and pCT images: (a) pCT images; (b) iCBCT images; (c) profiles on the orange line in (a) and (b), display window [1 000, 200] (color online)

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危及器官 Organ at risk	剂量体积限值 Dose volume limits
膀胱 Bladder	V₅₀<50%
直肠 Rectum	V₅₀<40%，V₄₀<50%
股骨头 Femoral head	V₄₀<5%，D_max<52 Gy
小肠 Small intestine	V₅₀<10%，D_mean<30 Gy
卵巢 Ovary	D_max<12 Gy
睾丸 Testis	D_max<4 Gy

Table 1. Dose volume limits of organ at risk (OAR)

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参数Parameter	D₂ / cGy	D₉₈ / cGy	D_mean / cGy	CI	HI
pCT	6 255±84	5 895±57	6 116±74	0.877±0.034	0.059±0.016
CBCT	6 287±71	5 875±53	6 074±95	0.860±0.035	0.068±0.017
t	-1.599	1.346	1.918	-2.065	1.837
p	>0.05	>0.05	>0.05	>0.05	>0.05

Table 2. Results of target dosimetric parameters

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参数Parameter		D_mean / cGy	D₅ / cGy	V₂₀ / %	V₃₀ / %	V₄₀ / %
左股骨头 Left femoral head	pCT	2 222±166	3 177±285	74.66±6.26	18.76±7.22	1.65±0.82
	CBCT	2 224±169	3 163±285	73.96±6.34	19.04±7.35	1.63±0.81
	t	-0.053	0.195	0.428	-0.151	0.095
	p	>0.05	>0.05	>0.05	>0.05	>0.05
右股骨头 Right femoral head	pCT	2 125±246	3 005±468	75.28±8.99	15.25±8.50	1.94±0.92
	CBCT	2 122±247	2 997±467	74.69±8.94	15.16±8.49	1.95±0.93
	t	0.035	0.069	0.253	0.042	-0.073
	p	>0.05	>0.05	>0.05	>0.05	>0.05
直肠 Rectum	pCT	2 725±428	4 305±543	59.19±11.33	38.60±10.97	21.02±10.06
	CBCT	2 762±428	4 458±558	60.09±11.66	39.23±11.16	21.14±10.29
	t	-0.339	-0.368	-0.301	-0.223	-0.042
	p	>0.05	>0.05	>0.05	>0.05	>0.05
膀胱 Bladder	pCT	3 772±167	4 589±573	97.23±2.31	73.81±5.88	45.01±7.54
	CBCT	3 834±173	4 619±570	96.16±2.47	75.09±5.94	45.72±7.69
	t	-1.422	-0.209	1.752	-0.840	-0.367
	p	>0.05	>0.05	>0.05	>0.05	>0.05

Table 3. Results of OARs dosimetric parameters

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