According to development trend of air-to-air missiles to multi-tasking attack,we proposed an air-ground integrated fire control and attack technique.Analysis was made to the process of air-ground integrated combat.Then,an adaptive guidance law for missiles was established based on the traditional air-to-air and air-to-surface guidance modes,which is applicable to fire control of air-ground multi-tasking integrated combat.Taking the current performance of missiles,the relative situation between missiles and targets,and targets value into consideration,a task-switching decision-making function was established based on the TOPSIS,to make the missile attack the optimal target.The simulation results show that with this guidance approach,the missile can adaptively select the optimum guidance mode in the attacking process,and complete the guidance to the specified target based on the mission requirements.It can also make the missile change the target in its flying process.