By use of aspheric optical elements,a portable Fundus Fluorescein Angiography(FFA) camera is designed based on Gullstrand-Le Grand eye model. According to the principle of selecting filter, a B-2A filter combination from Nikon is used as the filter system to filter spectrum in this design, and the coaxial illumination system combined with an annular stop is designed to remove the stray light caused by a cornea to light the eyeground uniformly.An eye model is used in the design of photographic system to correct comprehensive aberrations from both the optical systems of human eye and the camera and to realize a high definition image with 2 mega pixels in all fields of view.The photographic system of the camera includes two aspheric surfaces, and it reduces the system from 9 lenses to 7 lenses. The result shows that this camera has strong ability for accommodation and adapts to different eyes from -12 m-1 to +12 m-1. The field of view of this camera is 30°, the resolution at the image surface is 120 lp/mm, and the distortion value is less than 3.9%. Because of the application of aspheric elements, the structure, volume and weight of the camera are optimized, and the image quality is improved.