This paper intended to prepare high-strength pipe concrete using autoclaved curing, while the concrete with standard curing was used as control sample. The influences of the stone powder replacement rate (granite stone powder/(granite stone powder+ground） sand, by mass), and the stone powder content (granite stone powder/(granite stone powder+cement), by mass) without adding ground sand on the strength of the pipe high-strength concrete were conducted, respectively. The types and morphological characteristics of hydration products of pipe high-strength concrete with granite powder were investigated by XRD and ESEM. The results show that under autoclaved curing, the concrete strength increases first, and then decreases with the increase of stone powder replacement rate and stone powder content. The strengths of the concretes are highest when the stone powder replacement rate is 25% and the stone powder content is 20%, respectively. The SiO2 in the granite powder has a pozzolanic reaction with Ca(OH)2 (cement hydration product) and produce tobermorite under autoclaved condition, and consequently the concrete become more compact. Therefore, the strength of concrete under autoclave curing at 3 d is higher than that of the concrete under standard curing at 28 d in the same mix ratio.