The three-cycle minimum surface (TPMS) structure has excellent mechanical and biomedical properties. By designing and manufacturing suitable TPMS bone scaffold structure,it provides the possibility for the clinical treatment of bone repair,bone replacement and bone healing. Based on the structure parameters of human bone tissue,TPMS scaffolds with three main types of P,G and D and the fusion TPMS scaffolds with different fusion coefficient K values were designed respectively. The ceramic billets were prepared by UV stereophotolithography (SLA),and the molded alumina ceramic scaffolds were obtained through degrease and post-sintering treatment. The results show that: 1) the ceramic bracket has a relatively smooth surface and high molding accuracy,and its overall shape is basically consistent with the design model,and the side surface is slightly rougher than the top surface. 2) Compared with the single-type structure,the fused TPMS structure shows better compressive strength and stress distribution. When the fusion coefficient K=4,the mechanical properties of the P and G fusion scaffold are the best,the compressive strength is 71.72 MPa,and the maximum stress and average stress are 141.90 and 13.214 MPa,respectively. 3) The permeability of fusion structures is weaker than that of single-type structures,and the permeability of scaffolds with different fusion coefficient K values is also different. Combined with numerical simulation and experimental data,when the fusion coefficient K=1 or 2,the permeability of scaffolds with P and G structures and P and D structures is better. In conclusion,when the fusion coefficient K=1,the fusion scaffold with P and G structure has better mechanical properties and permeability,so it is suitable for the structure type of human bone scaffold.