PbSe quantum dots,6.5nm,10nm and 15nm,were synthesized in polyvinyl alcohol by in-situ synthesis method, the holographic performance of photopolymer doped PbSe quantum dots was researched. The three sizes of PbSe quantum dots with different concentration were incorporated in photopolymer,and inorganic-organic hybrid photopolymer films were prepared.It can be seen from the UV-Vis absorption spectrum of composite photopolymer films that the incorporation of PbSe quantum dots do not react with other components to produce new substance.Transmittance of hybrid photopolymer films were measured by Argon-krypton ion laser with a wavelength of 647 nm,as well as the diffraction efficiency and the Bragg mismatch of holographic recording grating.It can be obtained that the hybrid photopolymer films are uniform and PbSe quantum dots disperse well by transmittance curves.The anti-wrinkle effect of hybrid photopolymer films is due to the PbSe quantum dots which play a supportive role in the photopolymer chain,so that the strain is difficult to generate in the holographic recording process,and the photopolymer films anti-wrinkle capability is increased.The incorporation of PbSe quantum dots improve the diffraction efficiency compare with un-doped samples from diffraction efficiency curves.Additionally,there exists the optimum size and concentration of PbSe quantum dots,the maximum diffraction efficiency of samples can be raised from 67.2% to 89.7%,the volume shrinkage can be depressed to 0.8% under conditions that the average size of PbSe quantum dots is about 10 nm and the concentration of PbSe quantum dots is 3.6×10-6 mol/L.In conclusion,the incorporation of PbSe quantum dots greatly improve the holographic performance of materials.