Acoustic detection sensor system based on quartz-enhanced photoacoustic spectroscopy (QEPAS) with double acousticmicro-resonators (AmR) is developed. The experiment for detection of H2 O and CO2 was carried out to evaluate the sensitivity and stability of the system. The results show that the noise characteristics of the double AmR configuration still agree with the single AmR configuration. The double AmRs spectrophone configuration exhibits a strong acoustic coupling between the AmRs and the quartz tuning fork, which results in about 5 ms fast response time. The normalized noise equivalent absorption coefficients (NNEAs) of the top and bottom channels are 7.8×10-9 cm-1W/√Hz and 8.1×10-9 cm-1W/√Hz, respectively. Moreover, the double AmRs provide two independent detection channels that allow optical signal addition or cancellation from different optical wavelengths and facilitate rapid multigas sensing measurements.