PbSe quantum dot doped bare-optical fibers are prepared in laboratory by drawing sodium-aluminum-borosilicate-silicate-glass fusant and annealing heat treatment. The fibers are in the diameter of 80~130 μm. Transmission-electron microscope measurement shows that the prepared PbSe quantum dot in the fibers are in the diameter of 4.2~5.5 nm and with the doped volume ratio of 1%. The flexibility of Pbse quantum dot doped fibers is tested initially. The photoluminescence spectra of fibers are measured upon 980-nm pump by a fluorescence spectrometer. There is evidence to show that the available annealing condition of PbSe quantum dot fibers is different from PbSe quantum dot doped-bulk glass. When the annealing temperature is within 500~600 ℃ and the annealing time spans 5~10 h, the PbSe quantum dot fiber shows strongest photoluminescence emission, peaking wavelength ranging 1 300~1 450 nm and full width at half maximum coming to 200~330 nm. The optimum annealing temperature and time are 600 ℃ and 7.5 h, respectively. The PbSe quantum dot fibers obtained in this paper can be used to format PbSe-quantum-dot-doped-fiber gain devices based on glass (such as fiber amplifiers and fiber lasers) in the future.