A new type of multi-slit streak tube was designed with large efficient area,smaller bulk and lighter weight. By programming and Monte-Carlo simulation,even 10 mm off the axis,the spatial resolution can reach to 20 lp/mm,and the static physical temporal resolution can reach to 100 ps. On the basic of theoretical design,some processes were made such as the structural design,machining and assembly. A MS-Streak tube was manufactured. Its efficient photocathode area can reach ф22 mm. After testing with static experiment system set up,a static image with certain spatial resolution was obtained.