The data processing method for multi-pulse measured data in high frequency laser ranging is analyzed and researched, and a useful method is got by measuring pulse interval time using ground target ranging, adjusting transmitting epoch, screen processing and etc. Applied to process ranging data from 1.2 m telescope high frequency laser ranging system, it indicates efficient data increasing 10% at least, and root mean square hardly changing. This is significant to middle and high orbit satellites laser ranging data process where the echo signal is a few but there is muti-pulse measured data phenomenon.