It reports a series of new optical organic molecules of cinnamylidene acetophenone derivatives. We have synthesized eighteen compounds, and measured their powder second harmonic generation (SHG data 6~19 I2ω/I2ω urea), λ cut-off (450~510 nm) and λ max (320~380 nm). This series of molecules are found to have larger nonlinearity and shorter cut off wavelength than the chalcon derivatives. The experimental results indicate a promising application in low power lasers.