Contents
2016
Volume: 9 Issue 1
8 Article(s)

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Research Article
KillerRed protein based in vivo photodynamic therapy and corresponding tumor metabolic imaging
Qiaoya Lin, Shuang Sha, Fei Yang, Honglin Jin, and Zhihong Zhang
Photodynamic therapy (PDT) gains wide attention as a useful therapeutic method for cancer. It is mediated by the oxygen and photosensitizer under the specific light irradiation to produce the reactive oxygen species (ROS), which induce cellular toxicity and regulate the redox potential in tumor cells. Nowadays, genetic
Journal of Innovative Optical Health Sciences
  • Publication Date: Jan. 01, 1900
  • Vol. 9, Issue 1, 1640001 (2016)
Topical 5-aminolevulinic acid photodynamic therapy improved refractory acne conglobata and perifolliculitis capitis abscedens et suffodiens rather than hidradenitis suppurativa
Linglin Zhang, Peiru Wang, Lei Shi, Guolong Zhang, Yunfeng Zhang, Zhongxia Zhou, Zheng Huang, Hongwei Wang, and Xiuli Wang
Acne conglobata (AC), perifolliculitis capitis abscedens et suffodiens (PCAS) and hidradenitis suppurativa (HS) are uncommon refractory chronic, inflammatory, scarring diseases but cause serious damage to the quality of life. These three diseases are associated with follicular occlusion. Several studies indicated topic
Journal of Innovative Optical Health Sciences
  • Publication Date: Jan. 01, 1900
  • Vol. 9, Issue 1, 1640002 (2016)
Label-free imaging immune cells and collagen in atherosclerosis with two-photon and second harmonic generation microscopy
Chunqiang Li, Riikka K. Pastila, and Charles P. Lin
Atherosclerosis has been recognized as a chronic inflammation disease, in which many types of cells participate in this process, including lymphocytes, macrophages, dendritic cells (DCs), mast cells, vascular smooth muscle cells (SMCs). Developments in imaging technology provide the capability to observe cellular and t
Journal of Innovative Optical Health Sciences
  • Publication Date: Jan. 01, 1900
  • Vol. 9, Issue 1, 1640003 (2016)
Alterations of morphology of lymphoid organs and peripheral blood indicators under the influence of gold nanoparticles in rats
Alla B. Bucharskaya, Svetlana S. Pakhomy, Olga V. Zlobina, Galina N. Maslyakova, Olga V. Matveeva, Irina O. Bugaeva, Nikita A. Navolokin, Boris N. Khlebtsov, Vladimir A. Bogatyrev, Nikolai G. Khlebtsov, and Valery V. Tuchin
At present, gold nanoparticles (GNPs) are widely used in biomedical applications such as cancer diagnostics and therapy. Accordingly, the potential toxicity hazards of these nanomaterials and human safety concerns are gaining significant attention. Here, we report the effects of prolonged peroral administration of GNPs
Journal of Innovative Optical Health Sciences
  • Publication Date: Jan. 01, 1900
  • Vol. 9, Issue 1, 1640004 (2016)
Ultraviolet light A irradiation induces immunosuppression associated with the generation of reactive oxygen species in human neutrophils
Cunbo Li, Xuechen Shi, Mincai Chen, Guangxue Xu, Xinglei Su, Pengchong Jiang, and Leiting Pan
Ultraviolet blood irradiation has been used as a physical therapy to treat many nonspecific diseases in clinics; however, the underlying mechanisms remain largely unclear. Neutrophils, the first line of host defense, play a crucial role in a variety of inflammatory responses. In the present work, we investigated the ef
Journal of Innovative Optical Health Sciences
  • Publication Date: Jan. 01, 1900
  • Vol. 9, Issue 1, 1650001 (2016)
A robust automatic leukocyte recognition method based on island-clustering texture
Xiaoshun Li, and Yiping Cao
Journal of Innovative Optical Health Sciences
  • Publication Date: Jan. 01, 1900
  • Vol. 9, Issue 1, 1650009 (2016)