Contents
2021
Volume: 14 Issue 4
9 Article(s)

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Introduction to the special issue on surface-enhanced Raman spectroscopy and functionalized plasmonic nanoparticles for biomedical applications
Jian Ye, Haifeng Yang, and Nikolai Khlebtsov
Journal of Innovative Optical Health Sciences
  • Publication Date: Aug. 23, 2021
  • Vol. 14, Issue 4, 2102002 (2021)
Plasmonic nanoparticles and nucleic acids hybrids for targeted gene delivery, bioimaging, and molecular recognition
Timofey Pylaev, Elena Avdeeva, and Nikolai Khlebtsov
Promising biomedical applications of hybrid materials composed of gold nanoparticles and nucleic acids have attracted strong interest from the nanobiotechnological community. The particular interest is owing to the robust and easy-to-make synthetic approaches, to the versatile optical and catalytic properties of gold n
Journal of Innovative Optical Health Sciences
  • Publication Date: Aug. 23, 2021
  • Vol. 14, Issue 4, 2130003 (2021)
Optical penetration of surface-enhanced micro-scale spatial offset Raman spectroscopy in turbid gel and biological tissue
Yumin Zhang, Li Lin, Jing He, and Jian Ye
The limited penetration of photons in biological tissue restricts the deep-tissue detection and imaging application. The micro-scale spatially offset Raman spectroscopy (micro-SORS) with an optical fiber probe, colleting photons from deeper regions by offsetting the position of laser excitation from the collection opti
Journal of Innovative Optical Health Sciences
  • Publication Date: Aug. 23, 2021
  • Vol. 14, Issue 4, 2141001 (2021)
Differentiation of different antifungals with various mechanisms using dynamic surface-enhanced Raman spectroscopy combined with machine learning
Hao Li, Yongbing Cao, and Feng Lu
With the increase in mortality caused by pathogens worldwide and the subsequent serious drug resistance owing to the abuse of antibiotics, there is an urgent need to develop versatile analytical techniques to address this public issue. Vibrational spectroscopy, such as infrared (IR) or Raman spectroscopy, is a rapid, n
Journal of Innovative Optical Health Sciences
  • Publication Date: Aug. 23, 2021
  • Vol. 14, Issue 4, 2141002 (2021)
Surface-enhanced Raman spectroscopy of serum predicts sensitivity to docetaxel-based chemotherapy in patients with metastatic castration-resistant prostate cancer
Jianian Hu, Xiaoguang Shao, Chenfei Chi, Yinjie Zhu, Zhixiang Xin, Jianjun Sha, Baijun Dong, Jiahua Pan, and Wei Xue
Docetaxel-based chemotherapy, as the first-line treatment for metastatic castration-resistant prostate cancer (mCRPC), has succeeded in helping quite a number of patients to improve quality of life and prolong survival time. However, almost half of mCRPC patients are not sensitive to docetaxel chemotherapy initially. T
Journal of Innovative Optical Health Sciences
  • Publication Date: Aug. 23, 2021
  • Vol. 14, Issue 4, 2141006 (2021)
Synthesis and characterization of reporter molecules embedded core-shell nanoparticles as SERS nanotags
Chloe Duffield, Nana Lyu, and Yuling Wang
Surface-enhanced Raman scattering (SERS) spectroscopy is presented as a sensitive and speci fic molecular tool for clinical diagnosis and prognosis monitoring of various diseases including cancer. In order for clinical application of SERS technique, an ideal method of bulk synthesis of SERS nanoparticles is necessary t
Journal of Innovative Optical Health Sciences
  • Publication Date: Aug. 23, 2021
  • Vol. 14, Issue 4, 2141007 (2021)
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