By monitoring and analysis the ozone and meteorological observation data of the Yangtze River Delta, China, urban agglomeration in 2018, the temporal and spatial distribution characteristics of ozone and its correlation with meteorological elements in the region are studied.The results show that: (1) The ozone pollution in the Yangtze River Delta region shows the seasonal variation characteristics of high in spring and summer, and low in autumn and winter, and the ozone pollution in inland cities is more serious than that in coastal cities. (2) In the Yangtze River Delta region, inland cities mainly suffer from excessive pollution in summer, while coastal cities mainly in spring, and the number of daysof excessive ozone in inland cities is higher than that in coastal cities. (3) The daily variation of ozone is positively correlated with visibility, wind speed,and temperature, while negatively correlated with relative humidity. When the temperature is higher than 20°c, the relative humidity is between 20% and 60%, and the wind speed reaches 1.2 m·s－1 to 3.6 m·s－1, high-concentration ozone pollution is prone to occur. The research results have guiding significance for ozone joint prevention and control in the Yangtze River Delta.