High-precision image registration is the key to ensure the in-flight data validity of the Directional Polarimetric Camera (DPC). This paper introduces the polarization image registration method based on optical wedge and the multi-angle, multi-spectral image registration method based on earth reference grid. The error of the registration performance of the multi-angle and multi-spectral image of DPC are fully investigated, and the use of relative geometric calibration is applied to correct the error and improve the registration performance. To verify the effectiveness of this relative geometric calibration method, we compare the registration effects before and after error correction. The results reveal that the accuracies of DPC in flight multi-angle, multi-spectral and polarized image registration are better than 0.26 pixel, 0.14 pixel and 0.1 pixel respectively, which show an improvement of the registration performance.