The brightness uniformity and the crosstalk are the main factors which affect the applicability of the directional backlight lenticular-lens-based multiple autostereoscopic display. In this paper , by analyzing the causes of the generation of the crosstalk, according to the imaging optics principle of off-axis rays, the parameter calculating formula of the off-axis optical system which is consist of Liquid Crystal Display (LCD)panel column unit and cylindrical lens was derived. Then, a structure of butterfly-shaped LCD panel was proposed and used to design the module of the directional backlight autostereoscopic display. The simulation results show that, the directional backlight autostereoscopic 3D display backlight can eliminate the crosstalk. The crosstalk of the autostereoscopic display is less than 0.5% for the 90% viewing area of the view plane, the 10% peak width of the beam crosstalk area ratio is 0. The 90% peak width of the light beam is 1.37 times larger than that of the common liquid crystal cell structure, and the problem on the brightness of the image in different positions is improved.