In order to meet the requirements of modern high-tech warfare,reaction-jet/aerodynamic compound control and guidance technology can be used in missile control system to increase the mobility and accuracy of missiles.Firstly,the mathematical model of the missile in pitch plane is formulated,and the control law of reaction-jet and aerodynamics is designed separately by using switching control system.Secondly,the index reaching law and fuzzy control method are introduced to improve the accuracy of aerodynamic control.Simultaneously,the uncertain parameters design is optimized to enhance the effectiveness of reaction-jet control.At last,the simulation results show that the proposed scheme is very effective.