During the Sixteenth Guangzhow Asian Games multi-axis differential absorption spectrometers (MAX-DOAS)were used to monitor the atmospheric pollutants real-time in Guangzhou. As the atmospheric conventional and important pollutants, the daily change characteristics of SO2 and NO2 are discussed and further analyzed respectively. By combining meteorological conditions and the important pollution sources around Guangzhou the comprehensive regional pollution transport is analyzed. And it shows that the industrial area located in southeast of Guangzhou plays an important role in the pollution transport, among which SO2 is especially remarkable. The analysis of NO2 profile results shows that the pollutants mainly located in 1km below, and the high pollution layer mainly located in 0.5 km below.