In order to realize the high precision measurement of indoor moving target pose, a pose measurement system based on laser projection imaging was established. The system used pairwise collinear and crossover arranged on the same plane point laser projector as the cooperation target, the motion target pose measurement baseline amplification system was made up of cooperation target and laser projection point receiving curtain. Then, the high speed camera was used to real-time recording curtain projection light spot, and the world coordinates of projection spots were solved by the camera calibration results, the moving target pose calculation model was established using a unit vector that formed between projection spots. Finally, according to the measurement principle of target pose, the error transform function of image coordinate extraction, the external calibration parameters of camera and the beam straightness were deduced. The experimental results shows that when the cameras field-of-view is around 14 000 mm×7 000 mm, the attitude angle measuring accuracy of measurement system is 1′(1δ), the position is 5mm, and the target pose measurement error transfer function calculation. To verify the accuracy of the target pose measurement method proposed in this paper and the error transfer model, it can satisfy the target pose high precision requirements.