A new concept nanometer medicine molecular condensate macro-quantum system and its measurement method are postulated.According to the rationale that the feature of optical quantum can be characterized by photons,in which band-gap energies are more than that of nanometer medicine crystals by using 200nm~400nm and 350nm~850nm laser pumps,home-made optical system and measurement platform,therefore,the method of laser micro-photoluminescence spectrum for accurately measuring photoelectron coupling effect of nano-medicine crystals (optical quantum effect) is established.Experimental results reveal that the relative uncertainty of repeatedly measuring optical emission wavelengths by 14 times is 0% for optical quantum properties of nano-medicine crystals by laser micro-photoluminescence spectrum,which is smaller than the recommended 0.2% reference value of the national institute of Germany standard and technology (PTB),the measurement error of optical emission wavelengths is ［1-0］%,and that the relative uncertainty of repeatedly measuring optical emission intensities by 14 times is 5.1% for optical quantum properties of nano-medicine crystals by laser micro-photoluminescence spectrum,which is larger than the recommended 3% reference value of the National institute of standard and Technology (NIST),the measurement error of optical emission intensities is ［1+2.1］%.It is concluded that an accuracy measurement method of optical emission wavelengths and optical emission intensities by laser micro-photoluminescence spectrum solves two key issues of relative uncertainty and optical metrology traceability for a primary measurement standard,which will meet the wide needs of measuring photoelectron coupling effects or band-gap energies of electron structures for nano-bio-optical crystal macro-quantum state systems.