To evaluate the uncertainty of gear center measurement, evaluation method on uncertainty of gear center measurement based on quasi Monte-Carlo method (QMC) is proposed. The geometric errors are confirmed. The gear measurement model based on gear center measuremnt is established by coordinate transformation. The uncertainty of gear center measurement is evaluated by QMC, and the stability of this method is studied. The experiment shows that the evaluation proposed in this paper can accurately evaluate uncertainty of gear center measurement. The maximum deviation is 2.35%, so the method is stable.