Electronic penetration technology is used to establish a simulation system during penetration combat process, taking the typical intercontinental ballistic missile as a prototype and the missile defense system as a combat target. The simulation deductions with and without countermeasure methods of ballistic missile penetration are completed, and the feasibility and effectiveness of the detailed jamming methods in ballistic missile penetration is verified, which provide data support for the using of penetration measures, the selection of jamming time and the optimal analysis of the main technical characteristics of the jamming equipment in the real war.